VCAM1 anticorps

N° du produit ABIN967640

L’anticorps Souris Monoclonal anti-VCAM1 a été validé pour FACS, IP et IHC (fro). Il convient pour détecter VCAM1 dans des échantillons de Rat. Il y a 1 publication disponible.

Aperçu rapide pour VCAM1 anticorps (ABIN967640)

Antigène: VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

Reactivité: Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp VCAM1 est non-conjugé

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: MR106

Détail du produit anti-VCAM1 anticorps

Marque: BD Pharmingen™

Attributs du produit: 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogène: Rat VCAM-1-transfected L5178Y Cells

Isotype: IgG1 kappa

Information d'application

Indications d'application: Caution: Sodium azide is a reversible inhibitor of oxidative metabolism, therefore, antibody preparations containing this preservative agent must not be used in cell cultures nor injected into animals. Sodium azide may be removed by washing stained cells or plate-bound antibody or dialyzing soluble antibody in sodium azide-free buffer. Since endotoxin may also affect the results of functional studies, we recommend the NA/LE™ (No Azide/Low Endotoxin) antibody format for in vitro and in vivo use.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store undiluted at 4°C.

Références pour anticorps anti-VCAM1 (ABIN967640)

Bevilacqua: "Endothelial-leukocyte adhesion molecules." dans: Annual review of immunology, Vol. 11, Issue 4, pp. 767-804, (1993) (PubMed).

Détails sur VCAM1

Antigène: VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

Autre désignation: CD106

Sujet: The MR106 antibody reacts with CD106, the ~110 kDa transmembrane vascular cell adhesion molecule-1 (VCAM-1). Expression of CD106 on endothelial cells is induced by inflammatory cytokines and in certain pathologic conditions. In the rat bone marrow, CD106 has been reported to be expressed on dendritic cells and subsets of the myeloid lineage, but not detectable on peripheral leukocytes. CD106 has been reported to be a counter-receptor for VLA-4 (alpha4beta1 integrin) and alpha4beta7 integrin, and it plays an important role in leukocyte extravasation, particularly at sites of inflammation. This antibody is routinely tested by flow cytometric analysis.
Synonyms: VCAM-1

Pathways: Carbohydrate Homeostasis